Associate Scientist, High Throughput Screening/Assay Development (1 of 2)

  • Company: Johnson & Johnson
  • Location: Spring House, Pennsylvania
  • Posted: March 01, 2017
  • Reference ID: 8755170202-en-us

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for an Associate Scientist, High Throughput Screening/Assay Development, to be located in Spring House, PA. 

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. 

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.


The new Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams.  This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, enzymology, and screening technologies coupled with an ability to work collaboratively with internal and external partners.  Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as Associate Scientist in the Lead Discovery group.  This position will be based in Spring House, PA.

Job Description:

The candidate will be a key member of the High Throughput Screening group, and provide analytical support and expertise to therapeutic area programs from target nomination through declaration of a clinical candidate.

  • Design and perform biochemical or cell-based screening assays for HTS and Lead Generation
  • Utilize automation in the performance of HTS assays
  • Communicate results to project team members
  • Collaborate with Therapeutic Area scientists

The candidate will work closely with the Mechanistic and Cellular Pharmacology group to conduct Mechanism of Action studies with enzymes and their inhibitors. The candidate will provide screening expertise to internal programs as well as external collaborations.  The candidate will collaborate in a highly multidisciplinary/matrix environment for the progression of drug discovery projects. 


• B.S. with 4 or more years of experience, or M.S. with 3 or more years of experience in biochemistry, cell biology, chemistry or related areas.
• Expertise using methods such as luminescence, fluorescence, absorbance or radiometric detection assays to analyze biochemical or cell-based data.
• Experience in the design, optimization, and miniaturization of biochemical or cell based assays for High Throughput Screening is desired.
• Familiarity with modern automated laboratory instruments for running high throughput assays.
• Strong capabilities to collaborate with scientists in multiple disciplines is required.
• Excellent written and oral communication skills.
• Excellent quantitative analytical skills and familiarity with best practices in biochemistry and cell biology.
• Strong record of publications is desired.

Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID

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