Bioinformatics Associate Scientist II

  • Company: Johnson & Johnson
  • Location: Spring House, Pennsylvania
  • Posted: March 02, 2017
  • Reference ID: 3096170223-en-us

Janssen Research and Development, L.L.C., a member of Johnson and Johnson's Family of Companies, is recruiting for a Bioinformatics Associate Scientist II to be located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it. Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

We are looking for highly a motivated and experienced computational biologist to join us as an associate II scientist in Hybridoma/Molecular Biology group in Biologics Research. A successful candidate will be part of the team to support our antibody therapeutic discovery and development efforts. The focus of this position is application of bioinformatics tools and methods to the sequence analysis of large panel of mAbs cloned from hybridomas or single B cells from various immunized animal species, to establish informatics pipeline for Next Gene Sequencing (NGS) data analysis, and to maintain and update the internal databases. This person is also expected to interact with Janssen scientific staff, IT resources and external vendors to advance and deploy information technologies in antibody discovery. This position requires fluency in multiple computer languages, good knowledge in antibody structure and variable region sequences, familiar with antibody gene database such as IMGT and NCBI, and working knowledge of statistics.

Responsibilities include but are not limited to:
• Serving as the main computational biologist in Biologics Research for Antibody Discovery
• Partner with scientists across the organization to apply antibody structural knowledge and statistics to analyze large number of antibody sequences for therapeutic antibody generation
• Developing and applying bioinformatics tools for advancing internal technology platform for antibody discovery and antibody engineering and providing bioinformatics supports

• BS or MS in computational biology, Bio Technology or a related field is required
• 2-3 years of industry experience is preferred
• Demonstrated experience in quantitative analysis of high-volume biological datasets is preferred
• Fluent with multiple programming languages, for example Python programming language demonstrated ability to perform high-quality scientific programming is required
• Strong Linux/Unix OS skills is required
• Knowledge of NGS sequence analysis is preferred.
• Proficiency in various open source and commercial bioinformatics resources is preferred
• Working knowledge of laboratory techniques in molecular biology, cell biology and immunology is preferred
• Proven critical thinking skills and the ability to consider outcomes when designing analyses
• Excellence in record keeping is essential is required.

Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID

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