Drexel Co-op - Janssen R&D Biologics Clinical Pharmacology - Spring House, PA

  • Company: Johnson & Johnson
  • Location: Spring House, Pennsylvania
  • Posted: March 01, 2017
  • Reference ID: 7843161006-en-us

The co-op will support the BDS group, a part of Johnson & Johnson Pharmaceutical Research & Development, specifically within the Drug Metabolism Pharmacokinetics (DMPK) group. The DMPK group is responsible for the development of plate based assays in which ultimately determine pharmacokinetic profile of the drug in vivo. Prior to in vivo determination, plate based assays are developed and the student will aid in the reagent pairing process utilizing new technologies and various platforms.  The project will aim to cover both current and promising new practices within DMPK in order to explore potential process improvements thus making development time more efficient. 

The primary responsibility for this position will be:

  • To develop and validate immunological methods for supporting nonclinical and clinical PK studies under GLP guidelines.
  • Assay trouble shooting, development of new technology platforms (SPARCL, Singulex, etc.) and assay automation. 
  • A couple of projects available to work on are:
  1. Multiplexing hybrid LCMS/MS PK Assays for simultaneous drug monitoring in noncling/clinical to support pre-/post-NME efforts
  2. PK assay workflow modifications for improved efficiency and sensitivity using assay plates with covalent binding surfaces

  • The ideal candidate should be enrolled in BS/MS program in life sciences or a related scientific discipline with some relevant laboratory experience.
  • The individual must be motivated with a strong desire and interest in learning laboratory and scientific techniques in the Pharmaceutical R&D environment.
  • The candidate must be able to work with human and animal blood, body fluids and tissues. 
  • The successful candidate must have excellent: computer, record keeping, writing and communication skills.
  • Students must be able to provide their own transportation to/from their work location.
  • Students must be legally authorized to work in the United States and not require future sponsorship for employment visa status (e.g. H1-B status) now or in the future.

Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function

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