Expert Scientist, Substance & Antigen Expression
Location:
Rockville , Maryland
Posted:
December 15, 2017
Reference:
WD137882
Basic qualifications:
• MSc plus 8 years of industry experience or PhD
• Degree in RNA biology, virology or other vaccinology related discipline.
• R&D experience in application of DNA and RNA expression platforms toward recombinant protein expression and vaccine antigen development in an industrial, academic or government laboratory setting
• Understanding of different protein expression platforms, cell transfection/transduction and selection, experience with transient and stable expression systems
• Plasmid and viral vector design and optimization
• Experience with bioanalytical assay execution (ELISA, Flow Cytometry, PCR assays, DNA sequencing technologies)

Preferred qualifications:
• PhD degree.
• Core expertise in RNA biology, structural analytics, RNA vector design and optimization
• Excellent communication skills, ability to effectively interface with internal and external partners
• Ability to efficiently manage uncertainty, changes in priority and timeline restrictions
• Hands-on experience with development, evaluation and(or) implementation of new approaches for generation and characterization of stable cell lines expressing recombinant vaccine antigens and/or viruses used for clinical and commercial development of vaccine candidates
• Knowledge of GMP or GLP standards applicable to laboratory processes
• Learning agility, self-starter's attitude

Details:
Technical expert within the antigen expression group.

KEY RESPONSIBILITIES

• Supervises laboratory set-up activities
• Builds laboratory systems within a new organization
• Trains and mentors junior staff
• Oversees/ participates in the execution of laboratory activities
• Supports cell line development, viral, VLP, RNA and DNA vaccine development activities
• Works with minimal supervision in a matrix environment and effectively manage multiple projects
• Leads internal and external project and technology transfer activities
• Incorporates new technologies or techniques to refine the established antigen expression platforms
• Executes and documents experiments/technical studies/tasks independently, maintaining good scientific practices
• Applies appropriate regulatory guidelines to the vaccine development, co-authors technical reports used in regulatory filings, interacts with health authorities to ensure successful registration vaccine candidates
• Contributes to scientific papers and internal reports

Contact information:

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