Head of Investigative Immunotoxicology, Biologics Toxicology
Location:
Spring House , Pennsylvania
Posted:
April 02, 2017
Reference:
8396170130-en-us

Janssen Research and Development (R&D), L.L.C., a member of Johnson & Johnson's Family of Companies, is seeking a Head of Investigative Immunotoxicology within the Biologics Toxicology organization located in Spring House, PA.  This is a new group/role within the Biologics Toxicology organization and the Head will report directly to the Vice President and Head of Biologics Toxicology.  The position is at the Senior Scientific Director level.

 
 

Janssen R&D, part of the Janssen Pharmaceutical companies of Johnson and Johnson (J&J), develops treatments that improve the health and lifestyles of people worldwide.  R&D areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine. For more about Janssen R&D, L.L.C., visit www.janssen.com/research-and-development.  Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion, J&J is proud to be an equal opportunity employer.

 

The Head of Investigative Immunotoxicology for Biologics Toxicology will be a part of Janssen BioTherapeutics (JBIO; visit www.janssen.com/biotherapeutics ) and will support the development of novel biologic therapies which may include first-in-class technologies, stem cell therapies, monoclonal and multi-specific antibodies, alternative scaffolds, nucleic acid therapeutics, and protein molecules. 

 

The Head of Investigative Immunotoxicology will establish a new group within Biologics Toxicology with the goal of evaluating potential immune system-related risks associated with our biotherapeutic pipeline.  The candidate will expand on existing laboratory efforts in this area and, working with Project Toxicologists, will provide strategic and scientific input to multidisciplinary Project Teams progressing biotherapeutics from discovery to first-in-human and beyond. The Investigative Immunotoxicology group will use both internal and external (Contract Research Organizations) resources to generate data to support risk assessment.  It is anticipated that the Investigative Immunotoxicology group will work to establish/develop novel assays/animal models to assist in understanding potential human risks associated with candidates in our biologics pipeline.

 

The Head of Investigative Immunotoxicology will be part of the Biologics Toxicology Senior Leadership Team.  In addition, the candidate in this role will be part of the Biologics Toxicology Scientific Advisory Board.  This Board is responsible for the review and approval of nonclinical safety strategies as well as major issue review and recommendations for resolution. 

 

The candidate will manage both PhD level and technical level staff.   They will also be responsible for the development of all employees within their group and within Biologics Toxicology by supporting the development of Human Resources Planning (HRP) programs including management development and training to meet current and future business needs and provide an environment, which encourages the company's commitment to equal employment opportunity and the value of a diverse work force.  The candidate will also have responsibility for budget, resource and timeline commitments for the group.

 

The Head of Investigative Immunotoxicology for Biologics Toxicology will have a desire for learning and innovation, and continue career development through participation in scientific meetings, and increase visibility for self, Janssen BioTherapeutics and J&J through publications, participation in external organizations, and presentations at major scientific, industry, and regulatory meetings.

 


Qualifications
 
  • Ph.D. in immunology, immunotoxicology, toxicology or related discipline (pharmacology, cell/tumor/molecular biology, or related field) and/or professional degree (DVM, VMD) with training or extensive experience in immunotoxicology, immunology or related biologic disciplines.
  • 12 + years of pharmaceutical/biotechnology research management or related experience in drug development is required; direct experience with risk assessment for biotherapeutics is required.
  • Knowledge of GLPs and Health Authority regulations and guidelines for the development of biologics (e.g. ICH, FDA, EMEA, PMDA) is required.
  • Proven track-record in leading complex scientific teams, including direct people management experience is required.
  • Exceptional diplomacy and negotiating skills is required.
  • This role requires excellent communication and interpersonal skills, a high level of organizational ability and attention to detail.
  • Recognized/Established expert in the area of Immunotoxicology is required.
  • Good communication skills, attention to detail, troubleshooting skills and ability to work effectively in a collaborative environment is required.
  • Strong scientific and technical skills including flow cytometry (particularly as applied to the immune system), immunoassays and expertise in animal and cell based models is required.
  • Ability to propose mechanistic hypotheses, design and oversee the execution of experiments is required.
  • Leading edge knowledge of principles, concepts and practices in Immunotoxicology Is required.
  • Some travel (domestic and international) may be required dependent on project needs.


Primary Location
United States-Pennsylvania-Spring House
Organization
Janssen Research & Development, LLC. (6084)
Job Function
Toxicology Research
Requisition ID
8396170130

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