• Company: Johnson & Johnson
  • Location: Spring House, Pennsylvania
  • Posted: March 25, 2017
  • Reference ID: 1399170214-en-us

Janssen, a member of Johnson & Johnson's Family of Companies, is recruiting a Pharmacokinetics, Dynamics and Metabolism Intern.  Janssen is the name given to Johnson & Johnson’s global group of pharmaceutical companies.  These companies market both conventional and biotech products in a broad range of therapeutic areas. The Internship Program is focused on providing university graduate students with practical industrial scientific experience.

This summer intern will:
  • Optimize and compare 2 co-cultured hepatocytes systems for maximum production of covalent protein binding of drugs incubated at 2 concentrations.
    • The turnover of drugs will be determined by radio-profiling of incubation extract and the solubilized washed-protein pellets will be analyzed by SDS-PAGE.
    • The radiolabeled protein band will be excised and in-gel digestion will be performed for protein identification using high resolution accurate mass LC-MS and searching protein database.

  • Candidates must be enrolled in an accredited college (not necessarily taking classes) and in their third or fourth year of a PhD program in Chemistry, Biochemistry, Pharmaceutical Chemistry, Medicinal Chemistry, Pharmacology, Toxicology, Pharmaceutical Sciences or a related discipline.
  • Looking for candidate with experience handling radioactivity, performing protein separation by SDS-PAGE, in-gel digestion for proteomic analysis by high resolution accurate LC-MS.
  • Students must be available for 3 or 4 consecutive months between May and October 2017 and have the ability to work full-time during that time.

Primary Location
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)
Job Function
Requisition ID

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