Scientist, DMPK
Location:
San Diego , California
Posted:
January 12, 2017
Reference:
1631160325-en-us

Janssen Research & Development, LLC, a Johnson and Johnson Company, is hiring a Scientist, DMPK to be located in La Jolla, CA.


Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com/ for more information.  


Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. We are proud to be an equal opportunity employer.


The Scientist, DMPK will:
  • Support drug discovery and early development efforts as a member and representative of the PDM (Pharmacokinetics, Dynamics and Metabolism) group working closely with other teams such as chemistry, biology, and toxicology.
  • Manage and/or conduct in vitro ADME studies using various matrices (e.g. liver microsomes, hepatocytes, blood/plasma).
  • Design and execute mechanistic experiments tailored to address project specific questions such as characterizing enzyme kinetics, investigating non-P450 metabolism (e.g. UGT- or AO-metabolism) and measuring tissue binding.
  • Perform bioanalytical method development and quantitation of discovery compounds in blood or tissue of preclinical species.
  • Develop and implement new assays. 


Qualifications
  • A BS or MS degree in Pharmaceutical Sciences or a related field with at least 8 years of relevant pharmaceutical industry experience is required.
  • Understanding of DMPK principles, experience in outsourcing and conducting various ADME assays and strong technical expertise in bioanalysis using LC-MS/MS systems (ABI Sciex) are required. 
  • Experience as a DMPK project team representative is a plus. 
  • The candidate must possess excellent interpersonal, organizational, oral/written communication and leadership skills.  
  • The position is located in La Jolla, CA and may require up to 10% travel.


Primary Location
United States-California-San Diego
Organization
Janssen Research & Development, LLC. (6084)
Job Function
R&D

A little about us:
Johnson & Johnson cares for the world - bringing innovative ideas, products and services to advance the health and well-being of people.

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