Janssen Research & Development, LLC., a Johnson and Johnson Company is hiring an Scientist, to be located in Malvern, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.
Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visithttp://www.janssenrnd.com/
for more information.
We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
The candidate for this position will lead and perform process development for the Cell Culture antibody processes within the API-Large Molecule group in Malvern, PA. The candidate’s primary responsibilities will include leading and participating in the design of experiments, executing the planned experiments, and optimizing the process steps to the target process scale. This will include laboratory and occasional pilot-scale scale bioreactors. Additional responsibilities include:
- Lead the design and execution of development studies to identify and determine appropriate ranges of (critical) process parameters for cell culture, to optimize growth and product production
- Record and analyze experimental data, verify data integrity and accuracy, and report/summarize findings to the project team, and also draft technical documents and perform technology transfer to collaboration partners
- Work in a team environment as well as contributing individually to meet project timeline and objectives
A PhD in Chemical Engineering or Biological Sciences or Biochemistry OR MS in Chemical Engineering or Biological Sciences or Biochemistry and with at least 9 years of relevant experience OR a BS in Chemical Engineering or Biological Sciences or Biochemistry and with at least 12 years of relevant experience is required
Knowledge of and hands-on experience in one of the following areas mammalian cell culture, bioreactors, bioreactor process development, and bioreactor data analysis is required
Knowledge and hands-on experience with downstream processing and purification of antibodies, in particular chromatography and filtration is preferred
Familiarity with and hands-on experience with analytical methods typically used in the manufacture and characterization of recombinant proteins is preferred
Experience maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required
Occasional weekend work is required as well as occasional work at a secondary facility in Springhouse, PA
Janssen Research & Development, LLC. (6084)Job Function