Senior Associate Scientist Immuno Assay
Location:
South San Francisco , California
Posted:
January 20, 2017
Reference:
R-29193
The department of PKDM within Amgen is dedicated to the discovery and development of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of novel therapeutic drug candidates to improve their pharmacological potential. PKDM works in close partnership with disciplines such as protein science, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to engineer promising clinical therapeutic candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.
Responsibilities:
Develop and routinely employ bioanalytical methods for the quantitative and qualitative analysis of new protein/mAb entities in plasma, tissues, and other biological matrices, as well as, interpret and provide bioanalytical results to project team representatives in support of drug discovery and development.
Independently design and execute experiments to quantitate molecular entities by immunoassay (ELISA, Gyros, MSD) in support of both drug discovery and early development programs.
Understand preclinical ADME and bioanalytical techniques
Work as a member of the bioanalytical group and will be responsible for sample preparation, tissue homogenization, affinity capture, data generation and analysis with Watson-LIMS
Assist in troubleshooting when instrument or assay problems arise
Basic bioanalytical research, electronic laboratory notebook keeping and communication of results to project teams.
Basic Qualifications:
Master's degree & 3 years of scientific experience
OR
Bachelor's degree & 5 years of scientific experience
Preferred Qualifications:
BS or MS in biology, chemistry, biochemistry, immunology or equivalent Experience with independent operation of various automated immunoassay platforms
Excellent oral and written communication skills
Work collaboratively in a fast-paced work environment
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.


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