Cancer progression is a manifestation of genetically induced changes in the dynamic interaction of many cellular components. To guide precision medicine discovery campaigns at Pfizer, the newly formed Cancer Systems Therapeutics group located in La Jolla will develop cutting-edge systems biology tools to quantify global cellular perturbations induced by oncogenic changes and by small molecules aimed at counteracting such changes. Team members will apply systems biology-based disciplines to identify novel intervention targets with genetic- and chemistry-first approaches and to deepen our understanding of anti-cancer programs under development. We are seeking an experienced cell biologist to contribute to the success of the systems biology group, with sound knowledge of target identification and validation in a drug discovery context. This is an exciting opportunity to apply cutting-edge methods and contribute to the target portfolios of the disease Research Units of one of the world's leading developers of novel therapeutics. Responsibilities Develop tool assets for advancing systems biology group projects including cell models of disease, chemical probe validation, and molecular library construction Work with and manage relationships with external contract providers Stay current with systems biology-relevant technologies including those relating to molecular and cell biology, and biochemistry Contribute to building a culture that embraces continuous learning and improvement Help to establish the systems biology group as an integral component of world-wide research development Qualifications Minimum Bachelor's degree plus at least 8 years' laboratory experience in an industrial or academic setting, preferentially master's degree in cell biology or related field plus at least 7 years' experience, or PhD with 1+ years' experience. Track record of successful contribution to research projects leading to advancement of projects. Significant experience with an array of molecular and cell biology methods, including cloning and vector construction, PCR-based expression analysis, and cell-based assays, and expertise in cell culture and lentiviral production. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. Additional Offer Details: Grade: 8 Eligible for Employee Referral Award A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the bio-pharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.