Manager, Analytics & Statistics Lead
Cambridge , Massachusetts
January 10, 2017

Shire is the leading global biotechnology company focusedon serving people with rare diseases and other highly specialized conditions.We strive to develop best-in-class products, many of which are available inmore than 100 countries, across core therapeutic areas including Hematology,Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders,Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and agrowing franchise in Oncology.

Our employees come to work every day with a sharedmission: to develop and deliver breakthrough therapies for the hundreds ofmillions of people in the world affected by rare diseases and other high-needconditions, and who lack effective therapies to live their lives to thefullest.

The Manager, GHEORE Analytics & Statistics leadposition within the department of Global Health Economics, Outcomes Researchand Epidemiology (GHEORE) is responsible for providing analytic and statisticalsupport for demonstrating the economic and humanistic value of Shire products.The position is responsible for assisting in the development of analytic andmodelling projects, and the communication of evidence generation to internaland external customers. The candidate is required to have hands-on experienceto implement appropriate economic and outcomes research analyses.

•Manage data extraction and manipulation of largerelational databases
•Provide recommendations and guidance regarding theappropriate data sources, study design, and statistical approaches to answeringkey research questions
•Perform descriptive and advanced statistical analysesusing datasets from clinical trials, prospective, observational studies, andlarge, retrospective databases (e.g., claims, EMR) in support of epidemiologicand health outcomes research.
•Develop health economic models including, but notlimited to, budget impact and cost effectiveness models to support thedemonstration of economic value
•Contribute to the development of abstracts, posters, andmanuscripts derived from departmental research



•Minimum Master's degree in statistics, biostatistics,mathematics, health economics, epidemiology, or other relevant field
•Minimum 1-3 years in health outcomes research, withpractical experience in claims data analysis
•Experience in patient reported outcomes researchpreferred
•Experience in economic model development preferred
•Intermediate publication experience

•Expert proficiency in SAS programming, includingperforming complex data manipulation and generating descriptive statistics.Experience with claims data or data with similar structure and complexity isnecessary.
•Work experience / knowledge of statistical methodscommonly used in health outcomes research, including statistical tests, GLMregression modeling techniques, GEE models, mixed models (multi-level models),survival analysis (Cox, parametric models), propensity score matching/modeling,meta-analysis, and indirect treatment comparison.
•Knowledge of building health economic decision modelsusing Excel/TreeAge
•Ability to write appropriate, detailed statisticalanalysis plans
•Ability to interpret and communicate results effectively
•Ability to think critically to develop appropriateanalytic solutions to research questions and problem-solve effectively
•Analyst may need to collaborate with HEORE leads to makenumerous decisions regarding how to handle data-related issues in order to adequatelyconduct analyses.
•Analyst will be required to make decisions regarding themost appropriate statistical approach to answering the research question.
•Overall rationale and approach to the analysis requiresapproval from the HEORE heads.

Equal Employment Opportunity
Shire is an equal opportunity employer. Shire evaluates qualified applicants without regard to race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, protected veteran status, disability/handicap status or any other legally protected characteristic.
EEO is the Law
EEO is the law - Supplement
Pay Transparency Policy
Reasonable Accommodations
Shire is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

A little about us:
At Shire, we help people with rare diseases and specialized conditions live their lives to the fullest.

Know someone who would be interested in this job? Share it with your network.